Rebecca J Willcocks

Rebecca J Willcocks,

Research Assistant Professor

Department: HP-PHYSICAL THERAPY
Business Phone: (352) 294-5997
Business Email: rw254@phhp.ufl.edu

Teaching Profile

Courses Taught
2020-2021
HSC4913 Supervised Research Experience
2019-2021,2023-2024
HSC4970 Public Health and Health Professions Senior Honors Thesis
2019-2024
OTH3413C Applied Kinesiology
2018
PHT6152C Exercise Physiology
2021,2024
HSC4905 Individual Study
2021-2024
PHT6153 Physiology for Pt
2022-2024
RSD6910 Supervised Research
2023-2024
RSD7979 Advanced Research
2024
RSD6940 Supervised Teaching

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-3383-0759

Publications

2024
Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy
Annals of Clinical and Translational Neurology. 11(1):67-78 [DOI] 10.1002/acn3.51933. [PMID] 37932907.
2023
Givinostat for Becker muscular dystrophy: A randomized, placebo-controlled, double-blind study.
Frontiers in neurology. 14 [DOI] 10.3389/fneur.2023.1095121. [PMID] 36793492.
2023
Multivariate modeling of magnetic resonance biomarkers and clinical outcome measures for Duchenne muscular dystrophy clinical trials.
CPT: pharmacometrics & systems pharmacology. 12(10):1437-1449 [DOI] 10.1002/psp4.13021. [PMID] 37534782.
2022
Characterization of patients with Becker muscular dystrophy by histology, magnetic resonance imaging, function, and strength assessments.
Muscle & nerve. 65(3):326-333 [DOI] 10.1002/mus.27475. [PMID] 34918368.
2022
Characterizing Expiratory Respiratory Muscle Degeneration in Duchenne Muscular Dystrophy Using MRI.
Chest. 161(3):753-763 [DOI] 10.1016/j.chest.2021.08.078. [PMID] 34536384.
2022
Development of Contractures in DMD in Relation to MRI-Determined Muscle Quality and Ambulatory Function.
Journal of neuromuscular diseases. 9(2):289-302 [DOI] 10.3233/JND-210731. [PMID] 35124659.
2022
Evaluating Genetic Modifiers of Duchenne Muscular Dystrophy Disease Progression Using Modeling and MRI.
Neurology. 99(21):e2406-e2416 [DOI] 10.1212/WNL.0000000000201163. [PMID] 36240102.
2022
Longitudinal changes in cardiac function in Duchenne muscular dystrophy population as measured by magnetic resonance imaging.
BMC cardiovascular disorders. 22(1) [DOI] 10.1186/s12872-022-02688-5. [PMID] 35681116.
2022
Step Activity Monitoring in Boys with Duchenne Muscular Dystrophy and its Correlation with Magnetic Resonance Measures and Functional Performance.
Journal of neuromuscular diseases. 9(3):423-436 [DOI] 10.3233/JND-210746. [PMID] 35466946.
2021
Assessment of rAAVrh.74.MHCK7.micro-dystrophin Gene Therapy Using Magnetic Resonance Imaging in Children With Duchenne Muscular Dystrophy.
JAMA network open. 4(1) [DOI] 10.1001/jamanetworkopen.2020.31851. [PMID] 33394000.
2021
Disease-modifying effects of edasalonexent, an NF-κB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial.
Neuromuscular disorders : NMD. 31(5):385-396 [DOI] 10.1016/j.nmd.2021.02.001. [PMID] 33678513.
2021
Walking activity in a large cohort of boys with Duchenne muscular dystrophy.
Muscle & nerve. 63(2):192-198 [DOI] 10.1002/mus.27119. [PMID] 33188573.
2020
Characterizing Enrollment in Observational Studies of Duchenne Muscular Dystrophy by Race and Ethnicity.
Journal of neuromuscular diseases. 7(2):167-173 [DOI] 10.3233/JND-190447. [PMID] 31929119.
2020
Conference report on contractures in musculoskeletal and neurological conditions.
Muscle & nerve. 61(6):740-744 [DOI] 10.1002/mus.26845. [PMID] 32108365.
2020
Lower Extremity Muscle Involvement in the Intermediate and Bethlem Myopathy Forms of COL6-Related Dystrophy and Duchenne Muscular Dystrophy: A Cross-Sectional Study.
Journal of neuromuscular diseases. 7(4):407-417 [DOI] 10.3233/JND-190457. [PMID] 32538860.
2020
Magnetic Resonance Imaging Studies in Duchenne Muscular Dystrophy: Linking Findings to the Physical Therapy Clinic.
Physical therapy. 100(11):2035-2048 [DOI] 10.1093/ptj/pzaa140. [PMID] 32737968.
2020
Modeling disease trajectory in Duchenne muscular dystrophy.
Neurology. 94(15):e1622-e1633 [DOI] 10.1212/WNL.0000000000009244. [PMID] 32184340.
2020
MR biomarkers predict clinical function in Duchenne muscular dystrophy.
Neurology. 94(9):e897-e909 [DOI] 10.1212/WNL.0000000000009012. [PMID] 32024675.
2020
Upper and Lower Extremities in Duchenne Muscular Dystrophy Evaluated with Quantitative MRI and Proton MR Spectroscopy in a Multicenter Cohort
Radiology. 295(3):616-625 [DOI] 10.1148/radiol.2020192210. [PMID] 32286193.
2019
Imaging respiratory muscle quality and function in Duchenne muscular dystrophy.
Journal of neurology. 266(11):2752-2763 [DOI] 10.1007/s00415-019-09481-z. [PMID] 31350642.
2019
Lower Extremity Functional Outcome Measures in Duchenne Muscular Dystrophy-A Delphi Survey.
Journal of neuromuscular diseases. 6(1):75-83 [DOI] 10.3233/JND-180337. [PMID] 30562905.
2019
Magnetic resonance imaging characteristics of injection site reactions after long-term subcutaneous delivery of drisapersen
European Journal of Pediatrics. 178(5):777-778 [DOI] 10.1007/s00431-019-03349-0. [PMID] 30790036.
2018
Leg muscle MRI in identical twin boys with duchenne muscular dystrophy.
Muscle & nerve. [DOI] 10.1002/mus.26081. [PMID] 29365354.
2018
Longitudinal timed function tests in Duchenne muscular dystrophy: ImagingDMD cohort natural history.
Muscle & nerve. 58(5):631-638 [DOI] 10.1002/mus.26161. [PMID] 29742798.
2018
Skeletal muscle magnetic resonance biomarkers correlate with function and sentinel events in Duchenne muscular dystrophy.
PloS one. 13(3) [DOI] 10.1371/journal.pone.0194283. [PMID] 29554116.
2018
Two-Year Longitudinal Changes in Lower Limb Strength and Its Relation to Loss in Function in a Large Cohort of Patients With Duchenne Muscular Dystrophy.
American journal of physical medicine & rehabilitation. 97(10):734-740 [DOI] 10.1097/PHM.0000000000000957. [PMID] 29734234.
2017
Magnetic resonance imaging of the proximal upper extremity musculature in boys with Duchenne muscular dystrophy.
Journal of neurology. 264(1):64-71 [DOI] 10.1007/s00415-016-8311-0. [PMID] 27778157.
2017
Multi-slice MRI reveals heterogeneity in disease distribution along the length of muscle in Duchenne muscular dystrophy.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology. 36(3):151-162 [PMID] 29774305.
2016
MRI quantifies neuromuscular disease progression.
The Lancet. Neurology. 15(1):26-8 [DOI] 10.1016/S1474-4422(15)00320-8. [PMID] 26549781.
2016
Multicenter prospective longitudinal study of magnetic resonance biomarkers in a large duchenne muscular dystrophy cohort.
Annals of neurology. 79(4):535-47 [DOI] 10.1002/ana.24599. [PMID] 26891991.
2014
Chemical shift-based MRI to measure fat fractions in dystrophic skeletal muscle.
Magnetic resonance in medicine. 72(1):8-19 [DOI] 10.1002/mrm.24917. [PMID] 24006208.
2014
Examination of effects of corticosteroids on skeletal muscles of boys with DMD using MRI and MRS.
Neurology. 83(11):974-80 [DOI] 10.1212/WNL.0000000000000775. [PMID] 25098537.
2014
Global T2 versus water T2 in NMR imaging of fatty infiltrated muscles: different methodology, different information, and different implications.
Neuromuscular disorders : NMD. 24(12):1120-1 [DOI] 10.1016/j.nmd.2014.07.002. [PMID] 25153266.
2014
Longitudinal measurements of MRI-T2 in boys with Duchenne muscular dystrophy: effects of age and disease progression.
Neuromuscular disorders : NMD. 24(5):393-401 [DOI] 10.1016/j.nmd.2013.12.012. [PMID] 24491484.
2014
Magnetic resonance imaging and spectroscopy assessment of lower extremity skeletal muscles in boys with Duchenne muscular dystrophy: a multicenter cross sectional study.
PloS one. 9(9) [DOI] 10.1371/journal.pone.0106435. [PMID] 25203313.
2013
Magnetic Resonance Imaging and Spectroscopy Detect Changes With Age, Corticosteroid Treatment, and Functional Progression in Dmd
Neuromuscular Disorders. 23(9-10) [DOI] 10.1016/j.nmd.2013.06.599.
2013
Skeletal muscles of ambulant children with Duchenne muscular dystrophy: validation of multicenter study of evaluation with MR imaging and MR spectroscopy.
Radiology. 269(1):198-207 [DOI] 10.1148/radiol.13121948. [PMID] 23696684.
2011
Design of a Multi-Center Study To Examine Skeletal Muscles of Children With Duchenne Muscular Dystrophy Using Mri/Mrs
Neuromuscular Disorders. 21(9-10):653-654 [DOI] 10.1016/j.nmd.2011.06.801.
2010
Age- and sex-related differences in muscle phosphocreatine and oxygenation kinetics during high-intensity exercise in adolescents and adults.
NMR in biomedicine. 23(6):569-77 [DOI] 10.1002/nbm.1495. [PMID] 20661873.
2010
Commentaries on Viewpoint: Do oxidative and anaerobic energy production in exercising muscle change throughout growth and maturation? The importance of exercise intensity when studying developmental energy metabolism.
Journal of applied physiology (Bethesda, Md. : 1985). 109(5):1565-6 [DOI] 10.1152/japplphysiol.00986.2010. [PMID] 21171239.

Grants

Sep 2021 ACTIVE
MR Biomarkers of Bone Quality in DMD
Role: Principal Investigator
Funding: US ARMY MED RES ACQUISITION
Sep 2021 ACTIVE
Optimizing Muscular Dystrophy Clinical Trial Designs using Modeling and Simulation
Role: Co-Investigator
Funding: NATL INST OF HLTH NCATS
Sep 2020 ACTIVE
Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Jul 2019 ACTIVE
OoR Matching Support for CTSI
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Oct 2017 – Feb 2020
A randomised, double blind, placebo controlled study to evaluate the micro-macroscopic effects on muscles, the safety and tolerability, and the efficacy of givinostat in patients with Becker Muscular Dystrophy
Role: Co-Investigator
Funding: ITALFARMACO S P A

Education

PhD
2007-2011 · University of Exeter
MSc
2006-2007 · University of Exeter
BSc
2000-2006 · University of Victoria

Contact Details

Phones:
Business:
(352) 294-5997
Emails:
Business:
rw254@phhp.ufl.edu
Addresses:
Business Mailing:
PO BOX 100154
DEPARTMENT OF PHYSICAL THERAPY
GAINESVILLE FL 326100154