Sean C Forbes

Sean C Forbes,

Associate Professor

Department: HP-PHYSICAL THERAPY
Business Phone: (352) 273-6111
Business Email: scforbes@phhp.ufl.edu

About Sean C Forbes

Sean Forbes, PhD is a Associate Professor in the Department of Physical Therapy. Sean completed his doctoral studies at the University of Western Ontario (School of Kinesiology), where his research focused on skeletal muscle bioenergetics using magnetic resonance spectroscopy (MRS). Following graduate studies, he completed post-doctoral fellowships with Dr. Ron Meyer at Michigan State University (Department of Physiology) and Drs. Krista Vandenborne and Glenn Walter in the Muscle Physiology Laboratory at the University of Florida. Sean’s primary research interests involve implementing novel MRI/MRS techniques to monitor the progression of disease and treatments in muscular dystrophies. His research utilizes a translational approach, and he is currently examining the effects of potential therapeutic interventions and exercise on skeletal muscle and cardiac function.

Teaching Profile

Courses Taught
2014-2025
PHT6153 Physiology for Pt
2009,2012-2025
HSC4970 Public Health and Health Professions Senior Honors Thesis
2018,2021
PHT6152C Exercise Physiology
2017,2023-2025
RSD6940 Supervised Teaching
2015
PHT6935C Seminar
2021,2023-2025
RSD7979 Advanced Research
2021
RSD7980 Research for Doctoral Dissertation
2021-2024
RSD6910 Supervised Research
2021
HSC4905 Individual Study
2024
RSD6938 Doctoral Seminar in Rehabilitation Science
2024-2025
RSD6905 Individual Work

Publications

Academic Articles
2024
Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy.
Annals of clinical and translational neurology. 11(1):67-78 [DOI] 10.1002/acn3.51933. [PMID] 37932907.
2022
Characterizing Expiratory Respiratory Muscle Degeneration in Duchenne Muscular Dystrophy Using MRI.
Chest. 161(3):753-763 [DOI] 10.1016/j.chest.2021.08.078. [PMID] 34536384.
2022
Commentaries on Viewpoint: Hoping for the best, prepared for the worst: can we perform remote data collection in sport sciences?
Journal of applied physiology (Bethesda, Md. : 1985). 133(6):1433-1440 [DOI] 10.1152/japplphysiol.00613.2022. [PMID] 36509417.
2022
Development of Contractures in DMD in Relation to MRI-Determined Muscle Quality and Ambulatory Function.
Journal of neuromuscular diseases. 9(2):289-302 [DOI] 10.3233/JND-210731. [PMID] 35124659.
2022
Effects of muscle damage on 31 phosphorus magnetic resonance spectroscopy indices of energetic status and sarcolemma integrity in young mdx mice.
NMR in biomedicine. 35(3) [DOI] 10.1002/nbm.4659. [PMID] 34841594.
2022
Evaluating Genetic Modifiers of Duchenne Muscular Dystrophy Disease Progression Using Modeling and MRI.
Neurology. 99(21):e2406-e2416 [DOI] 10.1212/WNL.0000000000201163. [PMID] 36240102.
2022
Insights into neuromuscular fatigue using 31 P-MRS.
The Journal of physiology. 600(13):3011-3012 [DOI] 10.1113/JP283331. [PMID] 35687052.
2022
Longitudinal changes in cardiac function in Duchenne muscular dystrophy population as measured by magnetic resonance imaging.
BMC cardiovascular disorders. 22(1) [DOI] 10.1186/s12872-022-02688-5. [PMID] 35681116.
2022
Step Activity Monitoring in Boys with Duchenne Muscular Dystrophy and its Correlation with Magnetic Resonance Measures and Functional Performance.
Journal of neuromuscular diseases. 9(3):423-436 [DOI] 10.3233/JND-210746. [PMID] 35466946.
2021
Assessment of rAAVrh.74.MHCK7.micro-dystrophin Gene Therapy Using Magnetic Resonance Imaging in Children With Duchenne Muscular Dystrophy.
JAMA network open. 4(1) [DOI] 10.1001/jamanetworkopen.2020.31851. [PMID] 33394000.
2021
Disease-modifying effects of edasalonexent, an NF-κB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial.
Neuromuscular disorders : NMD. 31(5):385-396 [DOI] 10.1016/j.nmd.2021.02.001. [PMID] 33678513.
2021
Postcontractile blood oxygenation level-dependent (BOLD) response in Duchenne muscular dystrophy.
Journal of applied physiology (Bethesda, Md. : 1985). 131(1):83-94 [DOI] 10.1152/japplphysiol.00634.2020. [PMID] 34013753.
2021
Safety, feasibility, and efficacy of strengthening exercise in Duchenne muscular dystrophy.
Muscle & nerve. 63(3):320-326 [DOI] 10.1002/mus.27137. [PMID] 33295018.
2021
The impact of statin therapy and aerobic exercise training on skeletal muscle and whole-body aerobic capacity.
American heart journal plus : cardiology research and practice. 5 [DOI] 10.1016/j.ahjo.2021.100028. [PMID] 34590057.
2020
31 P magnetic resonance spectroscopy in skeletal muscle: Experts’ consensus recommendations.
NMR in biomedicine. 34(5) [DOI] 10.1002/nbm.4246. [PMID] 32037688.
2020
Lower Extremity Muscle Involvement in the Intermediate and Bethlem Myopathy Forms of COL6-Related Dystrophy and Duchenne Muscular Dystrophy: A Cross-Sectional Study.
Journal of neuromuscular diseases. 7(4):407-417 [DOI] 10.3233/JND-190457. [PMID] 32538860.
2020
Modeling disease trajectory in Duchenne muscular dystrophy.
Neurology. 94(15):e1622-e1633 [DOI] 10.1212/WNL.0000000000009244. [PMID] 32184340.
2020
MR biomarkers predict clinical function in Duchenne muscular dystrophy.
Neurology. 94(9):e897-e909 [DOI] 10.1212/WNL.0000000000009012. [PMID] 32024675.
2020
Upper and Lower Extremities in Duchenne Muscular Dystrophy Evaluated with Quantitative MRI and Proton MR Spectroscopy in a Multicenter Cohort.
Radiology. 295(3):616-625 [DOI] 10.1148/radiol.2020192210. [PMID] 32286193.
2019
Age-dependent changes in metabolite profile and lipid saturation in dystrophic mice.
NMR in biomedicine. 32(5) [DOI] 10.1002/nbm.4075. [PMID] 30848538.
2019
Effects of PDE5 inhibition on dystrophic muscle following an acute bout of downhill running and endurance training.
Journal of applied physiology (Bethesda, Md. : 1985). 126(6):1737-1745 [DOI] 10.1152/japplphysiol.00664.2018. [PMID] 30946638.
2019
Imaging respiratory muscle quality and function in Duchenne muscular dystrophy.
Journal of neurology. 266(11):2752-2763 [DOI] 10.1007/s00415-019-09481-z. [PMID] 31350642.
2019
Magnetic resonance imaging characteristics of injection site reactions after long-term subcutaneous delivery of drisapersen.
European journal of pediatrics. 178(5):777-778 [DOI] 10.1007/s00431-019-03349-0. [PMID] 30790036.
2018
Leg muscle MRI in identical twin boys with duchenne muscular dystrophy.
Muscle & nerve. [DOI] 10.1002/mus.26081. [PMID] 29365354.
2018
Skeletal muscle magnetic resonance biomarkers correlate with function and sentinel events in Duchenne muscular dystrophy.
PloS one. 13(3) [DOI] 10.1371/journal.pone.0194283. [PMID] 29554116.
2018
Two-Year Longitudinal Changes in Lower Limb Strength and Its Relation to Loss in Function in a Large Cohort of Patients With Duchenne Muscular Dystrophy.
American journal of physical medicine & rehabilitation. 97(10):734-740 [DOI] 10.1097/PHM.0000000000000957. [PMID] 29734234.
2017
Contrast-Enhanced Near-Infrared Optical Imaging Detects Exacerbation and Amelioration of Murine Muscular Dystrophy.
Molecular imaging. 16 [DOI] 10.1177/1536012117732439. [PMID] 29271299.
2017
Magnetic resonance imaging of the proximal upper extremity musculature in boys with Duchenne muscular dystrophy.
Journal of neurology. 264(1):64-71 [DOI] 10.1007/s00415-016-8311-0. [PMID] 27778157.
2017
Magnetic Resonance Monitoring of Disease Progression in mdx Mice on Different Genetic Backgrounds.
The American journal of pathology. 187(9):2060-2070 [DOI] 10.1016/j.ajpath.2017.05.010. [PMID] 28826559.
2016
Age-related T2 changes in hindlimb muscles of mdx mice.
Muscle & nerve. 53(1):84-90 [DOI] 10.1002/mus.24675. [PMID] 25846867.
2016
Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle.
JCI insight. 1(21) [DOI] 10.1172/jci.insight.90341. [PMID] 28018975.
2016
MRI quantifies neuromuscular disease progression.
The Lancet. Neurology. 15(1):26-8 [DOI] 10.1016/S1474-4422(15)00320-8. [PMID] 26549781.
2016
Multicenter prospective longitudinal study of magnetic resonance biomarkers in a large duchenne muscular dystrophy cohort.
Annals of neurology. 79(4):535-47 [DOI] 10.1002/ana.24599. [PMID] 26891991.
2016
Near-Infrared Optical Imaging Noninvasively Detects Acutely Damaged Muscle.
The American journal of pathology. 186(10):2692-700 [DOI] 10.1016/j.ajpath.2016.06.019. [PMID] 27565039.
2016
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.
Journal of the American Heart Association. 5(8) [DOI] 10.1161/JAHA.116.003911. [PMID] 27506543.
2015
Exercise programs for people with dementia.
The Cochrane database of systematic reviews. 2015(4) [DOI] 10.1002/14651858.CD006489.pub4. [PMID] 25874613.
2015
Longitudinal Evaluation of Muscle Composition Using Magnetic Resonance in 4 Boys With Duchenne Muscular Dystrophy: Case Series.
Physical therapy. 95(7):978-88 [DOI] 10.2522/ptj.20140234. [PMID] 25592189.
2015
Magnetic Resonance Assessment of Hypertrophic and Pseudo-Hypertrophic Changes in Lower Leg Muscles of Boys with Duchenne Muscular Dystrophy and Their Relationship to Functional Measurements.
PloS one. 10(6) [DOI] 10.1371/journal.pone.0128915. [PMID] 26103164.
2014
Assessment of intramuscular lipid and metabolites of the lower leg using magnetic resonance spectroscopy in boys with Duchenne muscular dystrophy.
Neuromuscular disorders : NMD. 24(7):574-82 [DOI] 10.1016/j.nmd.2014.03.013. [PMID] 24798221.
2014
Chemical shift-based MRI to measure fat fractions in dystrophic skeletal muscle.
Magnetic resonance in medicine. 72(1):8-19 [DOI] 10.1002/mrm.24917. [PMID] 24006208.
2014
Examination of effects of corticosteroids on skeletal muscles of boys with DMD using MRI and MRS.
Neurology. 83(11):974-80 [DOI] 10.1212/WNL.0000000000000775. [PMID] 25098537.
2014
Gene transfer of arginine kinase to skeletal muscle using adeno-associated virus.
Gene therapy. 21(4):387-92 [DOI] 10.1038/gt.2014.9. [PMID] 24572791.
2014
Longitudinal measurements of MRI-T2 in boys with Duchenne muscular dystrophy: effects of age and disease progression.
Neuromuscular disorders : NMD. 24(5):393-401 [DOI] 10.1016/j.nmd.2013.12.012. [PMID] 24491484.
2014
Magnetic resonance imaging and spectroscopy assessment of lower extremity skeletal muscles in boys with Duchenne muscular dystrophy: a multicenter cross sectional study.
PloS one. 9(9) [DOI] 10.1371/journal.pone.0106435. [PMID] 25203313.
2013
Exercise programs for people with dementia.
The Cochrane database of systematic reviews. (12) [DOI] 10.1002/14651858.CD006489.pub3. [PMID] 24302466.
2013
Magnetic Resonance Imaging and Spectroscopy Detect Changes With Age, Corticosteroid Treatment, and Functional Progression in Dmd
Neuromuscular Disorders. 23(9-10) [DOI] 10.1016/j.nmd.2013.06.599.
2013
Mri Measures of Bone in Duchenne Muscular Dystrophy
Neuromuscular Disorders. 23(9-10) [DOI] 10.1016/j.nmd.2013.06.602.
2013
Promising Findings: the Effects of Physical Activity On Persons With Dementia
Gerontologist. 53(1)
2013
Skeletal muscles of ambulant children with Duchenne muscular dystrophy: validation of multicenter study of evaluation with MR imaging and MR spectroscopy.
Radiology. 269(1):198-207 [DOI] 10.1148/radiol.13121948. [PMID] 23696684.
2013
Tâ‚‚ mapping provides multiple approaches for the characterization of muscle involvement in neuromuscular diseases: a cross-sectional study of lower leg muscles in 5-15-year-old boys with Duchenne muscular dystrophy.
NMR in biomedicine. 26(3):320-8 [DOI] 10.1002/nbm.2851. [PMID] 23044995.
2012
Long-term restoration of cardiac dystrophin expression in golden retriever muscular dystrophy following rAAV6-mediated exon skipping.
Molecular therapy : the journal of the American Society of Gene Therapy. 20(3):580-9 [DOI] 10.1038/mt.2011.264. [PMID] 22146342.
2012
MRI/MRS evaluation of a female carrier of Duchenne muscular dystrophy.
Neuromuscular disorders : NMD. 22 Suppl 2(Suppl 2):S111-21 [DOI] 10.1016/j.nmd.2012.05.013. [PMID] 22980762.
2012
Use of skeletal muscle MRI in diagnosis and monitoring disease progression in Duchenne muscular dystrophy.
Physical medicine and rehabilitation clinics of North America. 23(1):1-10, ix [DOI] 10.1016/j.pmr.2011.11.004. [PMID] 22239869.
2011
Changes in muscle T2 and tissue damage after downhill running in mdx mice.
Muscle & nerve. 43(6):878-86 [DOI] 10.1002/mus.21986. [PMID] 21488051.
2011
Design of a Multi-Center Study To Examine Skeletal Muscles of Children With Duchenne Muscular Dystrophy Using Mri/Mrs
Neuromuscular Disorders. 21(9-10):653-654 [DOI] 10.1016/j.nmd.2011.06.801.
2011
Long-term systemic myostatin inhibition via liver-targeted gene transfer in golden retriever muscular dystrophy.
Human gene therapy. 22(12):1499-509 [DOI] 10.1089/hum.2011.102. [PMID] 21787232.
2010
Distribution of T2 in the Soleus Muscle of Children With Duchenne Muscular Dystrophy
Medicine and Science in Sports and Exercise. 42
2010
High Dose Statin Therapy Reduces Muscle Oxidative Capacity in Healthy Adults
Medicine and Science in Sports and Exercise. 42
2010
Nnls Analyses of Skeletal Muscle T2 in Children With Duchenne Muscular Dystrophy
Medicine and Science in Sports and Exercise. 42
2009
Comparison of oxidative capacity among leg muscles in humans using gated 31P 2-D chemical shift imaging.
NMR in biomedicine. 22(10):1063-71 [DOI] 10.1002/nbm.1413. [PMID] 19579230.
2009
Light therapy for managing cognitive, sleep, functional, behavioural, or psychiatric disturbances in dementia.
The Cochrane database of systematic reviews. (4) [DOI] 10.1002/14651858.CD003946.pub3. [PMID] 19821317.
2009
Phosphocreatine recovery kinetics following low- and high-intensity exercise in human triceps surae and rat posterior hindlimb muscles.
American journal of physiology. Regulatory, integrative and comparative physiology. 296(1):R161-70 [DOI] 10.1152/ajpregu.90704.2008. [PMID] 18945946.
2009
The postprandial increase in blood triglycerides has no direct effect on the brain BOLD response.
Human brain mapping. 30(3):749-56 [DOI] 10.1002/hbm.20543. [PMID] 18266244.
2008
Effects of recovery time on phosphocreatine kinetics during repeated bouts of heavy-intensity exercise.
European journal of applied physiology. 103(6):665-75 [DOI] 10.1007/s00421-008-0762-2. [PMID] 18481078.
2008
Physical activity programs for persons with dementia.
The Cochrane database of systematic reviews. (3) [DOI] 10.1002/14651858.CD006489.pub2. [PMID] 18646158.
2008
Short-term high-intensity interval training improves phosphocreatine recovery kinetics following moderate-intensity exercise in humans.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 33(6):1124-31 [DOI] 10.1139/H08-099. [PMID] 19088770.
2007
Effects of hyperventilation on phosphocreatine kinetics and muscle deoxygenation during moderate-intensity plantar flexion exercise.
Journal of applied physiology (Bethesda, Md. : 1985). 102(4):1565-73 [PMID] 17218429.
2007
Prior exercise delays the onset of acidosis during incremental exercise.
Journal of applied physiology (Bethesda, Md. : 1985). 102(5):1799-805 [PMID] 17303706.
2005
NaHCO3-induced alkalosis reduces the phosphocreatine slow component during heavy-intensity forearm exercise.
Journal of applied physiology (Bethesda, Md. : 1985). 99(5):1668-75 [PMID] 16002768.
Presentations
2023-03-23
Quantifying Fat Infiltration in Upper Extremity Muscles of Boys with DMD by Magnetic Resonance Imaging and Spectroscopy. (*Bellam P, Lopez C, Forbes SC, Willcocks RJ, Rooney WD, Triplett WT, Brandsema J, Finanger EL, Barnard AM, Lott DJ, Senesac CR, Sweeney HL, Walter GA, Vandenborne K.)
State / Refereed. Poster. University of Florida, Gainesville, Florida
2023-03-23
Quantitative Magnetic Resonance to Assess Respiratory Muscle Quality and the Relationship to Function in Men with Becker Muscular Dystrophy. (*Rock K., Barnard A., Willcocks RJ, Smith B., Prabhakaran S., Lott D., Forbes S, Rooney W, Daniels M, Walter GA, Vandenborne K.)
State / Refereed. Poster. University of Florida, Gainesville, Florida
2023-03-05
MRI fat fraction of arm and leg muscles is correlated with function in Becker muscular dystrophy. (*Willcocks RJ, Senesac CR, Lott DJ, Forbes SC, Barnard AM, Arpan I, Triplett WT, Daniels MJ, Rooney WD, Walter GA, Subramony SH, Chahin NS, Sweeney HL, Vandenborne K)
National / Refereed. Poster. Dallas, Texas.
2023-03-03
Givinostat in DMD: results of the Epidys Study with particular attention to MR measures of muscle fat fraction (Vandenborne K, Willcocks R, Walter GA, Forbes SC, Kan HE, Cazzaniga S, Bettica P., Mercuri E., McDonald C)
National / Refereed. Symposium. Dallas, Texas
2023-06-03
Fat fraction dependent decrease of muscle water T2 in Duchenne muscular Dystrophy is steeper in patients with faster disease progression. (*Baetscher E, Triplett W, Walter GA, Forbes S, Willcocks R, Barnard A, Mueller R, Vandenborne K, Rooney W., *denotes presenting author))
International / Refereed. Speech. Toronto, Canada
2023-06-03
Elevated Muscle Water T2 in Dystrophinopathy. ( *Walter GA, Barnard A, Forbes SC, Willcocks RJ, Baetscer E, Triplett W, Rooney W, Vandenborne K.)
International / Refereed. Poster. Toronto, Canada
2023-03-21
Optimizing clinical trials for Duchenne muscular dystrophy by quantitatively bridging a functional endpoint and each transverse relaxation time of five leg muscles measured by MRI. (*Yoon DY, Daniels MJ, Morales JF, Willcocks RJ, Triplett WT, Barnard A, Forbes SC, Walter G, Rooney WD, Vandenborne K, Kim S)
National / Refereed. Poster. Atlanta, Georgia
2023-03-23
Phosphocreatine Recovery Kinetics Following Plantar Flexion Exercise in Young Boys with Duchenne Muscular Dystrophy. (*Awale P, Lopez C, Taivassalo T, Vandenborne K, Walter GA, Forbes SC)
State / Refereed. Poster. Univerisity of Florida, Gainesville, Florida.
2023-03-15
Grant Writing Workshop. Invited panelist: F-Grants (*Forbes SC).
International / Invited. Workshop. Gainesville, Florida
2023-02-18
Noninvasive Methods to Measure Fat Infiltration and Performance in Upper Extremities of Boys with DMD (*Bellam P, Lopez C, Forbes SC, Willcocks RJ, Rooney WD, Triplett WT, Brandsema J, Finanger EL, Barnard AM, Lott DJ, Senesac CR, Walter GA, Sweeney HL, Vandenborne K)
National / Refereed. Poster. San Diego, California
2022-10-11
Minimum Clinically Important Difference in Magnetic Resonance Biomarkers in DMD (*Willcocks RJ, Barnard AM, Forbes SC, Triplett WT, Brandsema J, Finanger EL, Rooney WD, Kim S, Wang DJ, Lott DJ, Senesac CR, Walter GA, Sweeney HL, Vandenborne K)
International / Refereed. Poster. Halifax, Canada
2024-03-16
Forbes SC, Chase L, Taivassalo T. Assessing leg vascular responsiveness to tadalafil using MRI in boys with DMD: implications for adjuvant vasodilator therapy.
National / Refereed. Poster. Orlando
2024-03-16
Bomma M, Forbes SC, Coppola JA, Carmen L, Pant A, Berthy J, McCaffrey B, May J, Corti M, Shih R, Lott DJ. CPET provides physiologically valid, repeatable measures revealing impaired cardiac, ventilatory and muscular responses to peak effort exercise in DMD.
National / Refereed. Poster. Orlando, Florida
2024-03-16
Taivassalo T., Forbes SC, Lott DJ, Powers C, Bernier AV, Zingariello CD, Sladky JT, Walter GA, Willcocks RJ, Vandenborne K, Daniels MJ, Sweeney HL. The impact of twice-weekly low dose prednisone on the side-effect profile and muscle pathophysiology in DMD: preliminary findings.
National / Refereed. Poster. Orlando, Florida
2024-02-13
Awale P, Lopez C, Taivassalo T, Vandenborne K, Walter GA, Forbes SC. Relationship between skeletal muscle energetics and clinical functional measures in Duchenne muscular dystrophy.
National / Refereed. Poster. Boston, USA
2024-02-13
Rock K., Barnard A., Willcocks R., Smith B., Prabhakaran S., Lott D., Senesac C., Forbes SC, Walter GA, Vandenborne K. Using MRI to Assess Respiratory Muscle Function and Quality in Men with Becker Muscular Dystrophy
Regional / Refereed. Poster. Gainesville, Fl
2024-02-13
Rock K, Willcocks RJ, Barnard A, Lott DJ, Senesac S, Forbes SC, Rooney W, Subramony A, Chahin N, Walter GA, Vandenborne K.
National / Refereed. Poster. Boston, USA
2023-10-03
Vandenborne K, Willcocks R, Walter G, Forbes S, Cazzaniga S, Bettica P, Mercuri E, McDonald C. Givinostat in DMD: results of the Epidys study with particular attention to MR measures of muscle fat fraction.
International / Refereed. Speech. Charleston, USA
2023-10-03
Rock K, Willcocks R, Forbes S, Barnard A, Lott D, Smith B, Prabhakaran S, Rooney W, Daniels M, Subramony S, Chahin N, Walter G, Vandenborne K. Quantifying skeletal muscle fat fraction and function using whole body magnetic resonance imaging (MRI) in men with Becker muscular dystrophy. Neuromuscular Disorders
International / Refereed. Poster. Charleston, USA
2023-10-03
Awale P, Lopez C, Taivassalo T, Vandenborne K, Walter G, Forbes S. Energetics and acid-base status of skeletal muscle at rest and following isometric dorsiflexion and plantar flexion contractions in Duchenne muscular dystrophy
International / Refereed. Poster. Charleston, USA
2023-11-01
Vandenborne K, Willcocks R, Walter GA, Forbes SC, Kan HE, Cazzaniga S, Bettica P., Mercuri E., McDonald C. Givinostat in DMD: results of the Epidys Study with particular attention to MR measures of muscle fat fraction
International / Invited. Speech. Dortmund, Germany
2024-04-01
Vandenborne K, Willcocks R, Walter G, Forbes S, Cazzaniga S, Bettica P, Mercuri E, McDonald C. Givinostat in DMD: results of the Epidys Study with particular attention to MR measures of muscle fat fraction.
International / Refereed. Speech. Paris, France
2024-04-15
Chase L, Taivassalo T, Forbes SC. Effect of Tadalafil on Blood Oxygenation Level Dependent Magnetic Resonance Imaging of Microvasculature in Boys with Duchenne Muscular Dystrophy.
Regional / Refereed. Poster.
2024-03-29
Chase L, Forbes SC, Taivassalo T. Evaluating Tadalafil as a Modulator of Duchenne Muscular Dystrophy with MRI-BOLD.
Regional / Refereed. Poster. Gainesville, Florida
2024-03-21
Awale P, Lopez C, Taivassalo T, Vandenborne K, Walter GA, Forbes SC. Relationship between skeletal muscle energetics and clinical functional measures in Duchenne muscular dystrophy
Regional / Refereed. Poster. Gainesville, USA
2024-03-21
Cooper KJ, Forbes SC, Banks S, LaMonica T, Farmer K, Pozzi F. Reduced microvascular function in supraspinatus rotator cuff tears: Insights from post-contractile MRI-BOLD analysis
Regional / Refereed. Poster. Gainesville, Fl
2024-02-13
Bellam P, Lopez C, Forbes SC, Willcocks RJ, Rooney WD, Triplett WT, Brandsema J, Finanger EL, Barnard AM, Lott DJ, Senesac CR, Sweeney HL, Walter GA, Vandenborne K. Characterizing Muscle Quality at Loss of Ambulation in Duchenne Muscular Dystrophy Using MRI
National / Refereed. Poster. Boston, USA

Grants

Nov 2024 ACTIVE
MRI/MRS Markers of Skeletal Muscle Disease Progression and Vascular Function in Non-Ambulatory Individuals with DMD
Role: Principal Investigator
Funding: US ARMY MED RES ACQUISITION
May 2024 ACTIVE
MRI analysis of patients with Charcot-Marie-Tooth disease type 4J
Role: Principal Investigator
Funding: TALIA DUFF FOUNDATION dba CURE CMT4J
Sep 2023 ACTIVE
Countering sympathetic vasoconstriction during skeletal muscle exercise as an adjuvant therapy for DMD
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Sep 2021 ACTIVE
Magnetic resonance biomarkers of muscle degeneration in patients with rotator cuff tears
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Aug 2021 – Dec 2021
Analysis of ImmunoForge MRI Images of Mice
Role: Principal Investigator
Funding: IMMUNOFORGE
Jul 2021 – Jun 2023
Seven tesla preclinical MRI/S scanner for structural, functional and molecular imaging
Role: Other
Funding: NATL INST OF HLTH OD
Sep 2020 ACTIVE
Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Jul 2019 ACTIVE
Impact and Interplay of Corticosteroid Regimen and Exercise Training on DMD Muscle Function
Role: Co-Investigator
Funding: US ARMY MED RES ACQUISITION
Sep 2016 – Jul 2022
MR Assessment of Bioenergetics and Microvascular Function in Dystrophic Muscle
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAMS
Jun 2016 – Aug 2018
Development of Magnetic Resonance Imaging as an Endpoint in Myotonic Dystrophy Type 1
Role: Co-Investigator
Funding: WYCK FOUNDATION via MYOTONIC DYSTROPHY FOU
Sep 2015 – Sep 2020
Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Jun 2014 – Nov 2016
MRI Evaluation of Skeletal Muscle Vascular Function in Patients with Non-alcoholic FattyLiver Disease
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND

Education

Post-doctoral Associate
2009-2011 · University of Florida
Post-doctoral Fellow
2007-2008 · Michigan State University
PhD
2001-2006 · The University of Western Ontario
BPE (Concentration: Exercise Physiology)
1993-1997 · Univesity of Alberta

Contact Details

Phones:
Business:
(352) 273-6111
Emails:
Addresses:
Business Mailing:
PO BOX 100154
DEPARTMENT OF PHYSICAL THERAPY
GAINESVILLE FL 326100154