Andrew Judge, PhD
Andrew Judge, PhDAssistant Professor University of Florida Department of Physical Therapy Box 100154, UFHSC Gainesville, FL 32610 -0154 Phone: (352) 273-9220 Fax: (352) 273-6109 Email: arjudge@phhp.ufl.edu |
Andrew Judge is an Assistant Professor in the Department of Physical Therapy.
Dr. Judge received his bachelor’s degree from Loughborough University
in England before moving to the U.S. to pursue a Masters degree in Exercise
Physiology at McNeese State University in Louisiana and subsequently a PhD
in Exercise Physiology at the University of Florida. Afterreceiving his
PhD, Dr. Judge completed his post-doctoral training at Boston University
studying disuse muscle atrophy. During this time Dr. Judge was a National
Space and Biomedical Research Institute (NSBRI) Fellow.
Dr. Judge’s research is focused on understanding the molecular signaling
pathways leading to skeletal muscle atrophy caused by disuse (cast immobilization),
disease (cancer and peripheral arterial disease), sepsis and aging. In addition,
ongoing work in his lab seeks to understand the role that specific proteins
play in regulating muscle regrowth following atrophying conditions. Currently
funded projects are centered on the heat shock protein (Hsp) family, and
understanding the mechanisms by which Hsps regulate various signaling pathways
involved in the regulation of muscle mass. His lab uses genetic approaches
(gene transfer, transgenics, and knockouts) to manipulate specific proteins
within these signaling pathways and determine the effect on gene transcription,
muscle fiber size, and muscle function. Dr. Judge’s lab uses the translational
approach of studying cultured muscle cells, whole muscle, and human biopsies
to comprehensively address their research questions. Eventually, improved
understanding of the proteins that regulate muscle mass will lead to the
identification of targets for specific interventions.
(full CV)
